Koichiro Tatsumi Selected Research

Vascular Remodeling

12/2021	The Isoquinoline-Sulfonamide Compound H-1337 Attenuates SU5416/Hypoxia-Induced Pulmonary Arterial Hypertension in Rats.
7/2020	Gut microbiota modification suppresses the development of pulmonary arterial hypertension in an SU5416/hypoxia rat model.
1/2020	Protective role of endothelial progenitor cells stimulated by riociguat in chronic thromboembolic pulmonary hypertension.
11/2017	Endothelial cell-related autophagic pathways in Sugen/hypoxia-exposed pulmonary arterial hypertensive rats.
1/2016	Prominin-1/CD133 expression as potential tissue-resident vascular endothelial progenitor cells in the pulmonary circulation.
1/2014	Pentraxin3 in chronic thromboembolic pulmonary hypertension: a new biomarker for screening from remitted pulmonary thromboembolism.
7/2011	Inhalation of Stachybotrys chartarum evokes pulmonary arterial remodeling in mice, attenuated by Rho-kinase inhibitor.
12/2010	Reversible or irreversible remodeling in pulmonary arterial hypertension.
9/2006	Angiotensin-converting enzyme gene polymorphisms and prognosis in chronic thromboembolic pulmonary hypertension.

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Koichiro Tatsumi Research Topics

Disease

62	Pulmonary Hypertension 05/2024 - 05/2002
42	Neoplasms (Cancer) 01/2024 - 05/2002
28	Pulmonary Arterial Hypertension 05/2024 - 06/2004
23	Hypoxia (Hypoxemia) 07/2023 - 05/2002
23	Chronic Obstructive Pulmonary Disease (COPD) 01/2021 - 08/2002
17	Lung Injury 03/2024 - 01/2007
15	Interstitial Lung Diseases (Interstitial Lung Disease) 05/2024 - 01/2002
13	Pulmonary Fibrosis (Fibrosing Alveolitis) 05/2024 - 11/2014
13	Fibrosis (Cirrhosis) 03/2024 - 10/2011
13	Idiopathic Pulmonary Fibrosis 03/2024 - 06/2005
13	Obstructive Sleep Apnea 10/2023 - 03/2003
11	Inflammation (Inflammations) 01/2024 - 01/2005
11	Lung Neoplasms (Lung Cancer) 01/2021 - 06/2007
10	Mesothelioma 05/2018 - 05/2012
10	Carcinoma (Carcinomatosis) 03/2018 - 03/2002
9	Vascular Remodeling 12/2021 - 09/2006
9	Infections 01/2020 - 01/2004
9	Dyspnea (Shortness of Breath) 04/2019 - 01/2009
8	Emphysema 05/2024 - 08/2004
8	Lung Diseases (Lung Disease) 01/2024 - 08/2004
8	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2024 - 12/2002
7	Pneumonia (Pneumonitis) 07/2023 - 10/2011
6	Hemorrhage 01/2023 - 01/2015
5	Body Weight (Weight, Body) 07/2023 - 05/2002
5	Respiratory Insufficiency (Respiratory Failure) 03/2023 - 09/2016
5	Pulmonary Alveolar Proteinosis 01/2023 - 06/2010
5	Disease Progression 01/2020 - 01/2013
5	Hemoptysis 01/2020 - 09/2007
5	Apnea 01/2020 - 03/2005
5	Malignant Mesothelioma 01/2017 - 01/2008
4	Connective Tissue Diseases (Connective Tissue Disease) 01/2024 - 01/2014
4	Atherosclerosis 10/2023 - 03/2017
4	Familial Primary Pulmonary Hypertension 01/2021 - 01/2014
4	Adenocarcinoma 01/2015 - 12/2011
4	Neoplasm Metastasis (Metastasis) 01/2013 - 05/2002
3	Diabetes Mellitus 10/2023 - 11/2018
3	Cardiovascular Diseases (Cardiovascular Disease) 10/2023 - 01/2019
3	Heart Failure 04/2023 - 01/2014
3	Sarcoidosis (Schaumann Disease) 01/2022 - 01/2013
3	Pulmonary Edema 10/2020 - 03/2019
3	Adenocarcinoma of Lung 07/2017 - 12/2013
3	Asthma (Bronchial Asthma) 01/2017 - 11/2010
3	Hypercapnia 11/2016 - 02/2005
3	Lymphangioleiomyomatosis (Lymphangiomyomatosis) 05/2016 - 02/2004
3	Pathologic Constriction (Stenosis) 01/2016 - 02/2004

Drug/Important Bio-Agent (IBA)

13	Oxygen (Dioxygen)IBA 07/2023 - 03/2005
12	Bleomycin (Blenoxane)FDA LinkGeneric 04/2023 - 01/2008
12	Cisplatin (Platino)FDA LinkGeneric 03/2018 - 12/2005
11	Biomarkers (Surrogate Marker)IBA 01/2024 - 04/2008
9	CytokinesIBA 03/2024 - 06/2003
9	Proteins (Proteins, Gene)FDA Link 10/2023 - 02/2011
8	nintedanibIBA 03/2024 - 07/2017
8	Semaxinib (SU5416)IBA 07/2023 - 11/2007
6	LipopolysaccharidesIBA 03/2024 - 08/2014
6	AutoantibodiesIBA 10/2023 - 04/2008
6	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 01/2023 - 04/2008
6	GoldIBA 01/2017 - 12/2003
5	pirfenidoneIBA 03/2024 - 07/2017
5	Warfarin (Coumadin)FDA LinkGeneric 11/2023 - 01/2017
5	Epoprostenol (Prostacyclin)FDA LinkGeneric 01/2023 - 06/2004
5	AnticoagulantsIBA 01/2023 - 06/2011
5	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA 05/2022 - 11/2007
5	Anti-Bacterial Agents (Antibiotics)IBA 07/2020 - 08/2004
5	Adrenal Cortex Hormones (Corticosteroids)IBA 04/2018 - 11/2010
5	Fas Ligand Protein (Fas Ligand)IBA 01/2005 - 03/2002
4	RNA (Ribonucleic Acid)IBA 02/2024 - 09/2020
4	AntibodiesIBA 10/2023 - 01/2020
4	Vasodilator Agents (Vasodilators)IBA 07/2022 - 03/2019
4	InterleukinsIBA 01/2022 - 01/2012
4	Phosphodiesterase 5 InhibitorsIBA 01/2021 - 01/2012
4	p38 Mitogen-Activated Protein KinasesIBA 09/2020 - 12/2006
4	Tyrosine Kinase InhibitorsIBA 01/2020 - 12/2011
4	Cytotoxins (Cytolysins)IBA 01/2019 - 06/2004
4	MidkineIBA 09/2017 - 06/2015
4	SurvivinIBA 09/2017 - 06/2015
4	Diphosphonates (Bisphosphonates)IBA 12/2016 - 05/2012
4	Zoledronic Acid (Zometa)FDA Link 12/2016 - 05/2012
4	CaspasesIBA 06/2015 - 05/2012
4	SmokeIBA 08/2014 - 04/2007
3	Matrix Metalloproteinases (MMPs)IBA 03/2024 - 05/2002
3	Pulmonary Surfactant-Associated Protein D (Surfactant Protein D)IBA 01/2024 - 09/2017
3	AntigensIBA 10/2023 - 01/2002
3	Acetaminophen (Paracetamol)FDA LinkGeneric 01/2023 - 04/2014
3	Interleukin-6 (Interleukin 6)IBA 01/2022 - 01/2008
3	SteroidsIBA 01/2022 - 01/2015
3	EnzymesIBA 12/2021 - 06/2004
3	CollagenIBA 09/2020 - 10/2011
3	riociguatIBA 01/2020 - 09/2013
3	Metformin (Glucophage)FDA LinkGeneric 01/2017 - 07/2012
3	Endothelin Receptor AntagonistsIBA 12/2016 - 01/2012
3	lipoarabinomannan (LAM)IBA 05/2016 - 02/2004
3	MonocrotalineIBA 01/2016 - 12/2010
3	Pemetrexed (MTA)FDA Link 01/2015 - 07/2012

Therapy/Procedure

45	Therapeutics 05/2024 - 03/2003
20	Endarterectomy (Thromboendarterectomy) 04/2023 - 06/2008
15	Drug Therapy (Chemotherapy) 09/2019 - 01/2007
6	Lung Transplantation 07/2021 - 02/2004
5	Radiotherapy 09/2017 - 12/2002
4	Continuous Positive Airway Pressure 01/2020 - 03/2003
4	Aftercare (After-Treatment) 05/2019 - 12/2007